I would consider myself an new adopter of GTD. I have tried countless software packages both online/offline, hard/soft copy. I even started to write my own in coldfusion.
As of today, I am using Vitalist. Why you may ask? vitalist allows for an email inbox. Now using a combination of SlickRun, bMail, I now can very quickly get items into my Vitalist Inbox.
It is awesome. I will post very soon where my inspiration came from, as well as what i did to make this work.
Read this article. I’m using the tool for half a year now and simply love it! The coolest feature is managing your plans in it via email.